The Office of the United States Trade Representative is headed by (naturally) the United States Trade Representative, a Cabinet-level official with the rank of Ambassador, who is directly responsible to the President and the Congress.

2006-Present
Susan C. Schwab, United States Trade Representative

2005-2006
Rob Portman, United States Trade Representative

2001-2005
Robert B. Zoellick, United States Trade Representative

1997 - 2000
Charlene Barshefsky, United States Trade Representative

1993-1996
Michael Kantor, United States Trade Representative

1989-1993
Carla A. Hills, United States Trade Representative

1985-1989
Clayton K. Yeutter, United States Trade Representative

1981-1985
William E. Brock III, United States Trade Representative

1979-1981
Reubin O’D Askew, United States Trade Representative

1977-1979
Robert S. Strauss, Special Trade Representative

1975-1977
Frederick B. Dent, Special Trade Representative

1971-1975
William D. Eberle, Special Trade Representative

1969-1971
Carl J. Gilbert, Special Trade Representative

1967-1969
William M. Roth, Special Trade Representative

1962-1966
Christian A. Herter, Special Trade Representative